If you're back on VLC versions 2.0.x or 2.1.x, there's no reason not to upgrade that I could find, and several reasons to take the plunge. The interface, though in a glacial rate of development, is getting better.
Addendum: VLC 3.0
VideoLan is already hard at work on version 3.0. I'm hoping for a revamped interface, but all that's promised is hardware decoding and acceleration to more platforms, better support for mp4, adaptive streaming and TS streams, and partial ChromeCast integration.
Update: This story, originally published on July 13, 2012, has been completely updated with our first hands-on impressions of VLC 2.2.
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